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Senior IT Internal Auditor- Dallas, TX (Hybrid)

Remote role Full-time Open position

About the position At Caris, we understand that cancer is an ugly word—a word no one wants to hear, but one that connects us all. That’s why we’re not just transforming cancer care—we’re changing lives. We introduced precision medicine to the world and built an industry around the idea that every patient deserves answers as unique as their DNA. Backed by cutting-edge molecular science and AI, we ask ourselves every day: “What would I do if this patient were my mom?” That question drives everything we do. But our mission doesn’t stop with cancer. We're pushing the frontiers of medicine and leading a revolution in healthcare—driven by innovation, compassion, and purpose. Join us in our mission to improve the human condition across multiple diseases. If you're passionate about meaningful work and want to be part of something bigger than yourself, Caris is where your impact begins. Position Summary We are seeking an experienced and motivated Senior IT Internal Auditor to join our growing Internal Audit team. In this role, you will play a critical part in strengthening the Company’s IT control environment, leading Sarbanes-Oxley (SOX) IT compliance efforts, and advising the business on technology risks and control design. This is an excellent opportunity for a technically strong auditor who enjoys partnering with the business, taking ownership of audit engagements, and contributing to continuous improvement initiatives across IT, security, and operations.

Responsibilities

  • Lead and execute risk-based IT and integrated audit engagements, including SOX IT General Controls (ITGCs), operational, and compliance audits
  • Serve as a key contributor to the Company’s SOX IT compliance program, including walkthroughs, documentation, and control testing.
  • Develop and maintain audit documentation such as process narratives, risk and control matrices, audit programs, and workpapers.
  • Identify control gaps, assess root causes, and partner with management on remediation plans.
  • Perform operational and integrated audits to assess process efficiency and policy compliance.
  • Coordinate with external auditors and internal stakeholders to support audit requests.
  • Communicate audit results through clear written reports and presentations.
  • Track audit issues and remediation status and escalate as needed.
  • Support annual audit planning and IT risk assessment activities.
  • Leverage data analytics and emerging technologies to enhance audit effectiveness.

Requirements

  • Bachelor’s degree in Information Systems, Computer Science, Accounting, or a related field.
  • 3+ years of experience in IT audit, internal audit, or information technology.
  • Strong understanding of SOX and internal control frameworks (e.g., COSO).
  • Experience leading audit engagements or major workstreams.
  • Excellent communication and organizational skills.
  • Excellent analytical and problem-solving skills.
  • Strong attention to detail and accuracy.
  • Ability to work independently and as part of a team.
  • Capacity to handle multiple tasks and meet deadlines.
  • Ability to gather and interpret operational and financial data, prepare high-quality audit workpapers and reports, and deliver results collaboratively across departments.
  • Proficient in Microsoft Office Suite (Excel, Word, PowerPoint)
  • Professional certification or progress toward certification (e.g., CISA, CISSP).

Nice-to-haves

  • Experience in life sciences, biotechnology, healthcare, or laboratory environments.
  • Experience with audit management tools such as AuditBoard.
  • Exposure to data analytics, automation, or AI-enabled audit tools.
  • Big Four or large public accounting firm experience.

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